CASC3 anticorps (AA 225-275)

N° du produit ABIN7454451

Cet anticorps Lapin Polyclonal détecte spécifiquement CASC3 dans IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour CASC3 anticorps (AA 225-275) (ABIN7454451)

Antigène: CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASC3 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-CASC3 anticorps

Épitope: AA 225-275

Fonction: Rabbit anti-CASC3 Antibody, Affinity Purified

Homologie: Mouse,Rat,Bovine

Purification: Affinity Purified

Immunogène: between AA 225 and 275

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-CASC3 antibody A302-472A.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CASC3

Antigène: CASC3 (Cancer Susceptibility Candidate 3 (CASC3))

Autre désignation: CASC3

Sujet: Background: Cancer susceptibility candidate gene 3 protein (CASC3) is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. CASC3 is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles [taken from NCBI Entrez Gene (GeneID: 22794)].

ID gène: 22794

NCBI Accession: NP_031385

UniProt: O15234